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CEO Albert Bourla said in January that the market for GLP-1s a class of obesity and diabetes drugs that mimic a gut hormone to suppress a person's appetite could eventually grow to $90 billion, and the company wants to capture $10 billion of that segment with an oral treatment

This risk is especially relevant for patients who were already at risk for deficiencies before starting treatment

The unique challenges these medications present demand specific solutions tailored to the physiological changes they create

For example, if progressive motility improves but then plateaus, a rest period may restore sensitivity and improve later responses

Patients received semaglutide treatment (0.25 mg/week initially, escalated to 0.5 mg/week) for 12 weeks